>> Newsletter 2008
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Accurate Investigation of Infertility
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Appropriate Selection of Treatment Modalities
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What’s TMC
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In-Vitro Fertilisation (I.V.F.)
 

This is the original 'test tube' technique. The most common indication for this procedure is blocked or damaged Fallopian tubes.

IVF is offered for infertility problems which do not respond to conventional medical or surgical therapy. These include damaged fallopian tubes, endometriosis, semen abnormalities, unexplained infertility, or when a combination of factors prevent pregnancy. IVF is a process involving stimulating the development of multiple ova (eggs) which are then retrieved from the ovaries by ultrasound-guided needle puncture.

The eggs are then transferred to the laboratory where they are fertilized with the partner's sperm and are allowed to develop in special culture medium. The embryos that result are then replaced in the uterus where they will hopefully attach and develop further into a successful pregnancy.

Requirements

  • An adequate semen sample.
  • The production of 4 or more oocytes (eggs).
  1. Hormone treatment (superovulation) to ensure the development of several oocytes.
  2. Monitoring of follicular growth.
  3. Induction of ovulation.
  4. Transvaginal aspiration of oocytes, under sedation (intra-venous introduction of drugs for sedation).
  5. The sperm sample is collected approximately 1 hour before the aspiration of the oocytes.
  6. Oocytes are inseminated with the husband's sperm sample.
  7. Embryo development (2-5 days).
  8. Transvaginal transfer (no anaesthetic) of up to 4 embryos.
  9. Pregnancy test (10 to 13 days after transfer).

Number of visits to centre

  • 7 to 10 per cycle for the female
  • 2 visits for the male

Clinical pregnancy rate per embryo transfer at TMC Fertility Centre is 55.3%*

* 14th World Congress on In Vitro Fertilisation and 3rd World Congress on In Vitro Maturation, Montreal, Canada, Sept 2007
* 7th International Symposium of Preimplantation Genetic Diagnosis International Society Conference, Melbourne, Australia, June 2007 (preliminary result)
* Obstetrical and Gynaecological Society of Malaysia (OGSM) Annual Congress June 2007
 
     
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